HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols
Oliver H. Krämer
This fully updated edition provides a series of methods for how best to assess functions of histone deacetylases and acetyltransferases. The disease-relevance of dysregulated protein deacetylation by overexpressed or aberrantly activated histone deacetylases has spurred an intense search for novel and improved inhibitors of these enzymes, as reflected in this collection. Expert contributors explore the generation and evaluation of novel histone deacetylase inhibitors and new and improved techniques to assess acetylation-dependent molecular mechanisms in vitro and in vivo. Written for the highly successfulMethods in Molecular Biologyseries, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and up-to-date,HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Editionserves as an ideal guide for researchers seeking to further elucidate this vital area of study.
Authoritative and up-to-date,HDAC/HAT Function Assessment and Inhibitor Development: Methods and Protocols, Second Editionserves as an ideal guide for researchers seeking to further elucidate this vital area of study.
Tahun:
2022
Edisi:
2
Penerbit:
Humana Press
Bahasa:
english
Halaman:
508
ISBN 10:
1071627872
ISBN 13:
9781071627877
Nama siri:
Methods in Molecular Biology, 2589
Fail:
PDF, 18.84 MB
IPFS:
,
english, 2022
Amazon 
Barnes & Noble 
Bookshop.org 
Tukar fail
Lebih banyak hasil carian
Faedah lain 
Istilah utama
Koleksi pilihan
